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Academic Journal

Current management of uncommon EGFR mutations in non-small cell lung cancer.

  • Authors : Trinh JQ; Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska, United States. Electronic address: .; Abughanimeh O

Subjects: Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/genetics ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/pathology ; Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/Carcinoma, Non-Small-Cell Lung*/drug therapy

  • Source: Current problems in cancer [Curr Probl Cancer] 2024 Apr; Vol. 49, pp. 101064. Date of Electronic Publication: 2024 Feb 03.Publisher: Mosby Country of Publication: United States NLM ID: 7702986 Publication Model:

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Academic Journal

Discovery of N-Trisubstituted Pyrimidine Derivatives as Type I RET and RET Gatekeeper Mutant Inhibitors with a Novel Kinase Binding Pose.

  • Authors : Zhang L; Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, United States.; Moccia M

Subjects: Mutation*; Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*drug therapy ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: Journal of medicinal chemistry [J Med Chem] 2022 Jan 27; Vol. 65 (2), pp. 1536-1551.Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531

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Academic Journal

Overall Treatment Strategy for Patients With Metastatic NSCLC With Activating EGFR Mutations.

  • Authors : Hayashi H; Department of Medical Oncology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka, Japan. Electronic address: .; Nadal E

Subjects: Neoplasm Metastasis*; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*drug therapy ; Genes, erbB-1/Genes, erbB-1/Genes, erbB-1/*genetics

  • Source: Clinical lung cancer [Clin Lung Cancer] 2022 Jan; Vol. 23 (1), pp. e69-e82. Date of Electronic Publication: 2021 Oct 25.Publisher: Elsevier Country of Publication: United States NLM ID: 100893225 Publication Model:

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Academic Journal

ARID1A, ARID1B , and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.

  • Authors : Zhu G; Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.; Shi R

Subjects: Mutation*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*genetics ; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*drug therapy

  • Source: Frontiers in immunology [Front Immunol] 2021 Aug 26; Vol. 12, pp. 670040. Date of Electronic Publication: 2021 Aug 26 (Print Publication: 2021).Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Signaling levels mold the RAS mutation tropism of urethane.

  • Authors : Li S; Pharmacology and Cancer Biology, Duke University, Durham, United States.; Counter CM

Subjects: Genes, ras/Genes, ras/Genes, ras/*genetics ; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*genetics ; Mutation/Mutation/Mutation/*genetics

  • Source: ELife [Elife] 2021 May 17; Vol. 10. Date of Electronic Publication: 2021 May 17.Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Outgrowth of erlotinib-resistant subpopulations recapitulated in patient-derived lung tumor spheroids and organoids.

  • Authors : Banda M; Division of Genetic and Molecular Toxicology, US Food & Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas, United States of America.; McKim KL

Subjects: Mutation*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*genetics ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: PloS one [PLoS One] 2020 Sep 08; Vol. 15 (9), pp. e0238862. Date of Electronic Publication: 2020 Sep 08 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081

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Academic Journal

Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with BIM deletion polymorphism.

  • Authors : Arai S; Division of Medical Oncology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.; Takeuchi S

Subjects: Mutation*; Bcl-2-Like Protein 11/Bcl-2-Like Protein 11/Bcl-2-Like Protein 11/*genetics ; ErbB Receptors/ErbB Receptors/ErbB Receptors/*antagonists & inhibitors

  • Source: The journal of medical investigation : JMI [J Med Invest] 2020; Vol. 67 (3.4), pp. 343-350.Publisher: University of Tokushima School of Medicine Country of Publication: Japan NLM ID: 9716841 Publication Model: Print Cited Medium: Internet

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Academic Journal

Homologous recombination in lung cancer, germline and somatic mutations, clinical and phenotype characterization.

  • Authors : Kadouri L; Sharett institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, 91120, Israel. Electronic address: .; Rottenberg Y

Subjects: Germ-Line Mutation* ; Homologous Recombination* ; Mutation*

  • Source: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2019 Nov; Vol. 137, pp. 48-51. Date of Electronic Publication: 2019 Sep 12.Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer.

  • Authors : Wang H; School of Life Sciences and Technology, Tongji University, Shanghai 200092, China. Electronic address: .; Lv Q

Subjects: Molecular Targeted Therapy* ; Pharmacogenetics*; Lung Neoplasms/Lung Neoplasms/Lung Neoplasms/*drug therapy

  • Source: EBioMedicine [EBioMedicine] 2019 Nov; Vol. 49, pp. 106-117. Date of Electronic Publication: 2019 Oct 23.Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Homologous recombination and DNA repair mutations in patients treated with carboplatin and nab-paclitaxel for metastatic non-small cell lung cancer.

  • Authors : Owen DH; Division of Medical Oncology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, United States. Electronic address: .; Williams TM

Subjects: DNA Repair* ; Homologous Recombination* ; Mutation*

  • Source: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2019 Aug; Vol. 134, pp. 167-173. Date of Electronic Publication: 2019 Jun 17.Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet

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